Seizures and Meningitis
Seizure types, status epilepticus, and CNS infection
Seizure types
| Focal aware | Patient stays conscious; twitching, odd sensations |
| Focal impaired awareness | Staring, lip smacking, picking at clothes; confused afterwards |
| Generalized tonic-clonic | Stiffening (tonic) then jerking (clonic); possible incontinence, tongue biting; postictal confusion and sleepiness |
| Absence | Brief staring spells (seconds), mostly children |
| Myoclonic / atonic | Sudden jerks / sudden loss of tone ("drop attacks": helmet) |
Triggers: missed medications, sleep loss, alcohol or withdrawal, fever, low glucose or sodium, flashing lights.
Status epilepticus (seizure ≥5 min, or repeated without recovery)
- Airway, oxygen, side-lying, suction; check glucose.
- Benzodiazepine first: IV lorazepam, or IM midazolam (or intranasal/rectal options) if no IV.
- Then a second-line IV drug: levetiracetam, fosphenytoin, or valproate.
- Still seizing: anesthesia and intubation.
Teaching
Take medications on time, never stop suddenly; medical ID; no driving until cleared under state law; don't swim or bathe alone; folic acid if planning pregnancy; seizure diary.
Bacterial meningitis
- Fever, severe headache, stiff neck, light sensitivity, confusion, vomiting.
- Kernig's sign: pain when straightening the knee with the hip flexed. Brudzinski's sign: bending the neck makes hips and knees flex.
- Petechial or purple rash → meningococcal: emergency.
- Lumbar puncture: bacterial = cloudy CSF, high protein, low glucose, high WBCs. Viral = clear, normal glucose.
- Antibiotics immediately after blood cultures: don't delay for imaging or LP. Dexamethasone with or just before the first dose (pneumococcal).
- Droplet precautions until 24 h of effective antibiotics (meningococcal).
- Close contacts get preventive antibiotics.
- Quiet, dark room; HOB 30°; seizure precautions; watch for ↑ICP, SIADH, septic shock, hearing loss.
- Prevention: MenACWY, MenB, pneumococcal and Hib vaccines.
After lumbar puncture
Position side-lying, knees to chest (or sitting leaning forward) during the procedure. Afterwards: encourage fluids; report a headache that's worse when upright (CSF leak). Bed rest afterward is a facility preference, not proven to prevent headache.
Memory hook
Kernig = Knee. Brudzinski = Bend the neck.