A 10-year-old boy is brought by his mother to the PMHNP for evaluation of a sudden onset of obsessions, compulsions, and tics. During the history and exam, the PMHNP learns that the child recently had strep throat. What is the most likely diagnosis?

Choice A reason: Tourette’s syndrome involves chronic motor and vocal tics with onset typically before age 18, but it is not associated with sudden onset triggered by infection. Choice B reason: This is correct. PANDAS is characterized by the sudden onset of OCD and/or tics following a streptococcal infection, consistent with this child’s acute symptom onset. Choice C reason: Obsessive-compulsive disorder may present with gradual onset rather than abrupt onset after infection, making PANDAS a more accurate diagnosis in this scenario. Choice D reason: Neurodevelopmental disorders are typically chronic, pervasive conditions beginning early in development, not acute, post-infectious symptom clusters.