A 10-year-old child was diagnosed with migraine headaches at a previous visit. Initial treatment included behavioral modifications, lifestyle changes, and a nonsteroidal anti-inflammatory drug (NSAID). The child returns for follow-up and states that interventions are not relieving the headaches. The most helpful medication at this time would be:

Rationale: A. Acetaminophen with codeine is generally not recommended in children for migraines due to risks of respiratory depression, dependence, and variable metabolism. B. Tricyclic antidepressants may be used as preventive therapy for frequent or severe migraines but are not first-line for acute relief. C. Sumatriptan (Imitrex) is a selective serotonin receptor agonist used for acute migraine attacks in children and adolescents. It can provide effective relief when NSAIDs and lifestyle modifications fail. D. Chloral hydrate is a sedative-hypnotic and is not indicated for treating migraines.