A 14-year-old patient has been diagnosed with uncomplicated mononucleosis. The nurse practitioner should:

Rationale: A. Uncomplicated mononucleosis is generally self-limiting, and management focuses on symptom relief. Acetaminophen (or ibuprofen) can be used to manage fever and sore throat. B. Corticosteroids are reserved for severe complications, such as significant tonsillar hypertrophy causing airway obstruction, and are not indicated for uncomplicated cases. C. Adolescents with mononucleosis should avoid contact sports or strenuous activity for at least 3–4 weeks, as splenomegaly increases the risk of splenic rupture. D. Antibiotics like amoxicillin are not indicated and may cause rash in patients with Epstein-Barr virus infection, a hallmark of mononucleosis.