A 19-year-old girl sustained multiple long bone fractures as a result of a motor vehicle crash and now is at risk for fat embolism. Which of the following signs and symptoms strongly suggest fat embolism?

Choice A reason: Bradypnea and bradycardia are not characteristic of fat embolism; fat embolism typically produces compensatory tachycardia and tachypnea. Choice B reason: Although confusion and shortness of breath can occur, bradycardia and bradypnea are inconsistent with fat embolism syndrome. Choice C reason: Fat embolism syndrome often presents with tachypnea, tachycardia, restlessness, and a petechial rash, which reflect pulmonary, neurological, and dermatologic involvement, making this the classic presentation. Choice D reason: Decreased temperature is not a hallmark sign of fat embolism; fever may actually occur in some cases, but tachypnea, tachycardia, restlessness, and petechial rash are the strongest indicators.