A 22 kg patient has an ordered for cefazolin 500 mg IV every 6 hours. The safe dose is 50 mg/kg/day. Is the ordered dose safe for the patient?

Given: Patient weight = 22 kg Ordered dose = 500 mg IV every 6 hours (4 doses/day) Safe dose = 50 mg/kg/day Step 1: Calculate the maximum safe daily dose Maximum safe dose = 50 mg/kg/day × 22 kg 50 × 22 = 1100 mg/day Step 2: Calculate the ordered daily dose Ordered dose = 500 mg per dose × 4 doses/day 500 × 4 = 2000 mg/day Step 3: Compare the ordered dose with the maximum safe dose Maximum safe dose = 1100 mg/day Ordered dose = 2000 mg/day 2000 mg/day > 1100 mg/day → not safe