A 26-year-old woman in her 37th week of pregnancy tested positive for Group B Strep. To prevent passing the infection to her newborn, how will she be treated?

Choice A reason: Oral antibiotics are not effective for intrapartum prophylaxis because they do not achieve adequate levels in the maternal bloodstream during delivery to prevent neonatal infection. Choice B reason: Administering antibiotics prior to labor may reduce maternal colonization but does not provide reliable protection for the neonate at the time of delivery. Choice C reason: Birth canal washes with chlorhexidine have been studied but are not considered effective or standard for preventing neonatal Group B Streptococcus transmission. Choice D reason: This is correct. Intrapartum IV antibiotic prophylaxis, typically with penicillin or ampicillin, is the recommended method to prevent vertical transmission of Group B Streptococcus to the newborn. Administering antibiotics during labor achieves adequate maternal and fetal concentrations at the time of birth.