A 56-year-old female client has discovered a new breast lump. The practical nurse (PN) recognizes that this client's greatest risk for a diagnosis of breast cancer is related to which factor?

A. While postmenopausal use of herbal estrogen may be a risk factor for breast cancer, it is not as significant as having a family history of the disease. B. A history of fibrocystic changes and a painful lump are not as strong a risk factor for breast cancer as a family history of the disease. C. Being of normal weight, height, and having children at a younger age are generally considered protective factors rather than risk factors for breast cancer. D. A non-tender lump combined with a family history of breast cancer (mother with breast cancer) is the most significant risk factor for developing breast cancer.