A child is diagnosed with acquired aplastic anemia. The nurse knows that this child has the best prognosis with which treatment regimen?
Explanation & Rationale
Rationale: A. Immunosuppressive therapy:This is a common treatment for aplastic anemia when a matched donor is unavailable, especially in older children and adults. However, it is less curative and carries a higher risk of relapse compared to bone marrow transplantation. B. Chemotherapy: Chemotherapy is not the primary treatment for aplastic anemia. It is mainly used in malignancies. In some cases, chemotherapy may precede transplantation or be part of immunosuppressive therapy, but it is not curative alone. C. Bone marrow transplantation: This is the treatment of choice and offers the best prognosis, particularly in children with a matched sibling donor. It provides a potential cure by replacing the defective marrow with healthy stem cells. D. Blood transfusions: Transfusions manage symptoms and prevent complications like anemia or bleeding but do not treat the underlying cause. Long-term use increases the risk of iron overload and alloimmunization.