Hesi rn dosage calculation proctored exam
Calculation
A child weighing 52.5 pounds receives a prescription for asparaginase 4,780 IU IV. The vial is labeled, "Asparaginase 10,000 IU single use vial. For intramuscular (IM) use, reconstitute in 2 mL sterile sodium chloride, and for IV use, reconstitute in 5 ml." How many mL should the nurse administer? (Enter the numeric value only. If rounding is required, round to the nearest tenth.)
mL
Explanation & Rationale
Desired dose = 4,780 IU Determine the available concentration for IV use after reconstitution: Available concentration = 10,000 IU / 5 mL = 2,000 IU/mL Calculate the volume to administer: Volume to administer (mL) = Desired dose (IU) / Available concentration (IU/mL) = 4,780 IU / 2,000 IU/mL = 2.39 mL Round to the nearest tenth: Rounded volume = 2.4 mL
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