A child weighing 52.5 pounds receives a prescription for asparaginase 4,780 IU IV. The vial is labeled, "Asparaginase 10,000 IU single-use vial. For IM use, reconstitute in 2 mL sterile sodium chloride, and for IV use, reconstitute in 5 mL". How many mL should the nurse administer? (Enter the numeric value only. If rounding is required, round to the nearest tenth.)

Step 1 is to identify the ordered dose and the correct available concentration based on the route of administration. Ordered Dose: 4,780 IU Route: IV (Intravenous) Available Strength: 10,000 IU Reconstitution Volume for IV: 5 mL Step 2 is to calculate the volume to administer in milliliters (mL) Volume = (Ordered Dose ÷ Available Dose) × Available Volume Volume = (4,780 ÷ 10,000) × 5 4,780 ÷ 10,000 = 0.478 0.478 × 5 = 2.39 Volume to administer = 2.39 mL Step 3 is to round to the nearest tenth 2.39 rounds to 2.4 Answer: 2.4