A child who weighs 25 kg receives a prescription for isoniazid 10 mg/kg/day by mouth once a day. The bottle is labelled "Isoniazid Oral Solution, USP 50 mg per 5 mL." How many mL should the nurse administer? (Enter numerical value only. If rounding is required, round to the nearest whole number.)

Calculation: Calculate the Total Daily Dose in milligrams (mg/day). Child's weight = 25 kg Prescribed dose = 10 mg/kg/day Total Daily Dose (mg/day) = Weight (kg) x Dose (mg/kg/day) = 25 kg x 10 mg/kg/day = 250 mg/day Calculate the Volume in milliliters (mL) to administer per dose Ordered Dose (D) = 250 mg Available Dose (H) = 50 mg Quantity (Q) = 5 mL Volume (mL) = (Dose Ordered (D) / Dose Available (H)) x Quantity (Q) = (250 mg / 50 mg) x 5 mL = 5 x 5 mL = 25 mL