A child who weighs 42 kg receives a prescription for methy/prednisolone succinate 5 mg/kg/day IV in divided doses every 6 hours. The medication is available in "Methy prednisolone succinate 40 mg/mL vials." How many mL. should the nurse administer with each dose? (Enter numerical value only. If rounding is required, round to the nearest tenth)
Explanation & Rationale
Given: Ordered dose of methylprednisolone succinate: 1.5 mg/kg/day IV in divided doses every 6 hours Child's weight: 42 kg Concentration of methylprednisolone succinate: 40 mg/mL Step 1: Calculate the total daily dose of methylprednisolone succinate: Total daily dose (mg) = Ordered dose (mg/kg/day) x Child's weight (kg) Total daily dose (mg) = 1.5 mg/kg/day x 42 kg Total daily dose (mg) = 63 mg/day Step 2: Calculate the dose per administration: Since the medication is given every 6 hours, there are 4 administrations per day. Dose per administration (mg) = Total daily dose (mg) / Number of administrations per day Dose per administration (mg) = 63 mg/day / 4 administrations/day Dose per administration (mg) = 15.75 mg Step 3: Calculate the volume to be administered per dose: Volume (mL) = Dose per administration (mg) / Concentration (mg/mL) Volume (mL) = 15.75 mg / 40 mg/mL Volume (mL) = 0.39375 mL Step 4: Round to the nearest tenth: Volume (mL) ≈ 0.4 mL