A child who weighs 66 pounds receives a prescription for amoxicillin 80 mg/kg/day by mouth (PO) in divided doses every 12 hours. The bottle is labeled, "Amoxicillin for Oral Suspension, USP 400 mg per 5 mL." How many mL should the nurse administer with each dose? (Enter numerical value only.)
Explanation & Rationale
First, we need to convert the child’s weight from pounds to kilograms since the dosage is prescribed in mg/kg. We know that 1 kg is approximately 2.20462 pounds. So, Weight in kg = Weight in pounds / 2.20462 = 2.2046266 ≈ 29.94kg The prescribed dosage is 80 mg/kg/day, so the total daily dosage in mg would be: Daily dosage in mg = Dosage per kg × Weight in kg = 80mg/kg × 29.94kg ≈ 2395.2mg The medication is to be administered in divided doses every 12 hours, so the dosage per dose in mg would be: Dosage per dose in mg = Daily dosage in mg/2 = 2395.2mg/2 ≈ 1197.6mg The medication is available in a concentration of 400 mg/5 mL. Therefore, the volume to be administered per dose in mL would be: Volume in mL = Dosage per dose in mg / Concentration in mg/mL = 1197.6mg / 80mg/mL ≈ 14.97mL So, the nurse should administer approximately 15 mL of Amoxicillin for Oral Suspension, USP per dose. Please note that this is a rounded value and the exact volume would be 14.97 mL.