A child with growth failure is receiving somatropin (rDNA origin) 1.25 mg subcutaneously (subQ) daily. The nurse reconstitutes the vial with 5 mL of bacteriostatic water for injection to yield a solution concentration of 5 mg/mL. How many ml. should the nurse administer? (Enter numeric value only. If rounding is required, round to the nearest hundredth.)

Here's why: We are given the specific dose of somatropin to administer: 1.25 mg (given). The volume to be administered depends solely on the prescribed dose and doesn't require the concentration for this case. Therefore, the nurse should administer 0.25 mL of the reconstituted somatropin solution. Calculation: Volume to administer (mL) = Dose (mg) / Concentration (mg/mL) However, we can rearrange the formula as long as we have the dose and target amount to administer: Volume to administer (mL) = Dose (mg) / Desired dose (mg/mL) In this case, the "Desired dose (mg/mL)" represents the concentration we want to administer, which is essentially the prescribed dose (1.25 mg) delivered in one injection. Volume to administer (mL) = 1.25 mg / 1.25 mg/mL Notice how the concentration units cancel out Volume to administer (mL) = 0.25 mL (round to nearest hundredth) Therefore, the nurse should administer 0.25 mL of the reconstituted somatropin solution subcutaneously.