A client diagnosed with Addison's disease is being treated with prednisone. The nurse must educate the patient about which of the following side effects of prednisone? Select all that apply.

Choice A reason: Prednisone, a corticosteroid, can suppress the immune system, making patients more susceptible to infections. This immunosuppressive effect is a significant concern, especially for patients with chronic conditions or those on long-term steroid therapy. Educating patients about the increased risk of infection is crucial for monitoring and preventing potential complications. Choice B reason: Hypotension is not typically a side effect of prednisone. In fact, prednisone can lead to fluid retention and increased blood pressure (hypertension), rather than decreased blood pressure. Therefore, educating the patient about hypotension is not necessary in the context of prednisone therapy. Choice C reason: Hypoglycemia, or low blood sugar, is not a common side effect of prednisone. On the contrary, prednisone can increase blood glucose levels, potentially leading to hyperglycemia. Patients with diabetes or those at risk for hyperglycemia need to be monitored and educated about this effect, rather than hypoglycemia. Choice D reason: Hypertension is a known side effect of prednisone due to its sodium-retaining and potassium-losing properties. This can lead to an increase in blood pressure, which is especially concerning for patients with cardiovascular conditions. Educating patients about the risk of hypertension helps in monitoring and managing this side effect. Choice E reason: Hyperglycemia is a common side effect of prednisone, especially in patients with diabetes or those predisposed to high blood sugar levels. Corticosteroids can increase glucose production and decrease insulin sensitivity, leading to elevated blood sugar levels. Patients should be informed about this risk and advised to monitor their blood sugar regularly.