A client diagnosed with chronic migraine headaches is considering acupuncture. The client asks a clinic nurse, "How does this treatment work?” Which is the best response by the nurse?

Choice A reason: Referring the client back to the acupuncturist avoids answering the question and does not provide therapeutic communication. Nurses should give accurate, evidence-based information when asked about treatments. Choice B reason: While serotonin and norepinephrine are involved in pain modulation, acupuncture is not specifically known to increase their production. This explanation is misleading and not supported by evidence. Choice C reason: Western medicine explains acupuncture as stimulating the release of endogenous opioids such as endorphins, which reduce pain perception. This is the most accurate and evidence-based explanation, making it the correct answer. Choice D reason: Suggesting HIV risk is inappropriate and inaccurate. Acupuncture performed with sterile, disposable needles carries minimal risk of infection. This response is fear-inducing and unprofessional.