A client diagnosed with major depressive disorder began taking escitalopram 5 days ago. The client now says, “This medicine isn’t working.” What is the nurse’s best intervention?

Choice A reason: As with Question 6, the most appropriate response is to educate the client about the expected delay in therapeutic effect. SSRIs require time to alter neurotransmitter levels and receptor sensitivity, and this explanation supports adherence and reduces frustration. Choice B reason: Reassurance alone does not provide the necessary information for the client to understand their treatment plan. It may be perceived as dismissive if not accompanied by education. Choice C reason: Dose changes should not be considered this early unless there are adverse effects or clinical deterioration. The standard protocol is to wait several weeks before evaluating the need for adjustment. Choice D reason: While monitoring for improvement is part of ongoing care, it is not the priority at day 5. The nurse should first ensure the client understands the expected timeline for symptom relief.