A client has a new prescription for a medication to be given via inhalation through a metered-dose inhaler (MDI). Which of the following education should the nurse include?

Choice A rationaleWaiting at least 5 minutes between puffs allows the first dose to take effect, optimizing absorption and reducing side effects when different inhaled medications are used.Choice B rationaleWaiting 10 minutes between puffs is unnecessary and might reduce adherence to treatment due to the prolonged interval.Choice C rationale"None of the above" does not provide a valid education point for using metered-dose inhalers.Choice D rationale"All of the above" is incorrect as it includes a recommendation that is not necessary (waiting 10 minutes). .