A client has an order for loperamide as needed (PRN). For which condition would the nurse administer this medication?

A. Abdominal pain: Loperamide is not indicated for isolated abdominal pain and may actually worsen symptoms if used inappropriately, especially if the pain is related to a bowel obstruction or inflammatory condition. B. Infection: While diarrhea may accompany infection, loperamide is typically avoided in infectious diarrhea, especially when caused by bacteria or toxins, because it can delay pathogen clearance and worsen the illness. C. Diarrhea: Loperamide is an antidiarrheal agent that slows intestinal motility, allowing more fluid absorption in the colon. It is commonly prescribed PRN for symptomatic relief of non-infectious diarrhea. D. Constipation: Administering loperamide in the setting of constipation would exacerbate the condition. It further reduces bowel motility, increasing the risk of fecal impaction or ileus.