A client has been administered phenobarbital during seizure activity. When assessing for adverse effects after resolution of the seizure, what assessment should the nurse prioritize?

A. Assessment of orientation: Phenobarbital can cause sedation and drowsiness, which may affect mental status, but orientation is not the immediate priority. Changes in alertness should be monitored after ensuring airway and breathing are stable. B. Evaluation of deep tendon reflexes: Depressed reflexes may occur with barbiturate use, but they are not the most critical concern following seizure resolution. Reflex checks are not typically prioritized unless overdose is suspected. C. Assessment for tetany: Tetany is usually linked to electrolyte imbalances, particularly hypocalcemia. Phenobarbital does not commonly cause tetany, so this is not a relevant or priority concern in this scenario. D. Focused respiratory assessment: Phenobarbital is a central nervous system depressant and may cause respiratory depression. Monitoring respiratory rate, depth, and oxygen saturation is crucial immediately after administration to ensure the client maintains adequate ventilation.