A client has been taking propylthiouracil (PTU) for 8 weeks. Which statement by the client would indicate the drug is having its desired effects? (Select all that apply).

A. Bruising is typically related to anticoagulant effects or blood disorders and not directly tied to the desired effects of PTU. B. Improved sleep is an indicator that hyperthyroidism symptoms, such as insomnia, are being managed effectively. C. A decrease in anxiety can suggest effective management of hyperthyroidism, as anxiety is a common symptom of this condition. D. Weight loss or inability to gain weight is usually a symptom of hyperthyroidism, so this statement would indicate that PTU is not achieving the desired effect. E. A return to regular menstruation can indicate improved thyroid function, as hyperthyroidism can disrupt menstrual cycles. F. Reduced heart rate and the absence of palpitations suggest effective management of hyperthyroidism symptoms, indicating the drug is having the desired effect.