A client is being discharged home after a kidney transplant with prescriptions for cyclosporine and prednisone. What priority education does the nurse provide with the client's discharge instructions?

A. Change positions slowly to avoid hypotension: This instruction is more relevant for clients taking antihypertensive medications or those at risk for orthostatic hypotension. While important in some cases, it is not the priority for a post-kidney transplant client on immunosuppressants. B. Use a soft-bristled toothbrush and avoid flossing: This education helps prevent gum bleeding and infection in immunosuppressed clients. It is important, but infection prevention in daily interactions has a broader impact and takes higher priority. C. Avoid large crowds and people who are sick: Cyclosporine and prednisone suppress the immune system, increasing susceptibility to infections. Avoiding exposure to sick individuals and crowded places is critical to prevent potentially life-threatening infections in the early post-transplant period, making this the priority teaching. D. Check your heart rate before taking the medication: Monitoring heart rate is relevant for medications affecting cardiac function, but neither cyclosporine nor prednisone routinely requires pre-dose heart rate checks. This instruction is lower priority compared with infection prevention.