A client is in the oncology clinic for a first visit since being diagnosed with cancer. The nurse reads in the client's chart that the cancer classification is TISNOMO. What does the nurse conclude about this client's cancer?

Rationale: A. The “N0” in the TNM classification means no regional lymph node involvement. If multiple lymph nodes were involved, the classification would read N1, N2, or N3, depending on the extent. B. The “M0” in the TNM staging system indicates no evidence of distant metastasis. This means the cancer has not spread to distant organs such as the lungs, liver, or bones. C. The “TIS” designation means Tumor In Situ, which identifies a localized, noninvasive cancer that has not spread beyond the epithelium of origin. The primary site is known. If the primary site were undetermined, the classification would use a Tx or unknown primary description. D. This would be indicated by Nx, not N0. “N0” means the lymph nodes were assessed and found to have no involvement.