A client is prescribed Methylprednisolone 5 mg/kg/day in four divided doses. The medication is supplied as 7.5 mg/5 mL. The client weighs 220 lbs. How many mL's will the nurse administer per dose? (Use a preceding zero if it applies. Do not use trailing zeros. Round to the nearest tenth)

Convert the client's weight from pounds to kilograms: 1 lb = 0.454 kg Weight in kg = 220 lbs x 0.454 kg/lb = 99.88 kg (approximately 100 kg) Calculate the total daily dose of Methylprednisolone: Daily dose = 1.5 mg/kg x 100 kg = 150 mg Calculate the dose per administration: The daily dose is divided into four equal doses. Dose per administration = 150 mg / 4 = 37.5 mg Determine the concentration of the Methylprednisolone: The medication is supplied as 7.5 mg per 5 mL. Concentration = 7.5 mg / 5 mL = 1.5 mg/mL Calculate the volume (in mL) to administer per dose: Use the concentration as a conversion factor: Volume (mL) = Dose per administration (mg) / Concentration (mg/mL) Volume (mL) = 37.5 mg / 1.5 mg/mL = 25 mL