A client is receiving a secondary infusion of vancomycin 1,500 mg in 250 mL to be infused over two hours. The IV administration set delivers 10 gtt/mL. How many gtt/min should the nurse regulate the infusion? (Enter numerical value only. If rounding is required, round to the nearest whole number.)

Determine the infusion rate in mL per hour: Total volume = 250 mL Total time = 2 hours Infusion rate = 250 mL ÷ 2 hours = 125 mL/hour Use the drop factor to calculate gtt/min: Drop factor = 10 gtt/mL Formula: gtt/min = (mL per hour × drop factor) ÷ 60 Calculation: (125 × 10) ÷ 60 = 20.83 gtt/min Round to the nearest whole number: Final answer = 21 gtt/min