A client is to receive Acyclovir 350 mg IV. You have available a 500 mg vial. Package directions tell you to reconstitute with 15 mL of sterile water. After withdrawing the required dose, further dilute in 100 mL of IV fluid to run over 1 hour. Calculate the rate to set the IV pump. (Round to the nearest tenth).

First, reconstitution only helps us get the correct dose, but the IV pump rate depends on the final volume and time. The medication is reconstituted and the prescribed 350 mg is withdrawn from the vial. That dose is then added to 100 mL of IV fluid to infuse over 1 hour. For IV pump settings, we use: Rate (mL/hr) = Total volume to infuse ÷ Time in hours Rate = 100 mL ÷ 1 hour Rate = 100 mL/hr Correct answer: 100.0 mL/hr