A client newly diagnosed with major depressive disorder is prescribed fluoxetine a selective serotonin reuptake inhibitor (SSRI). The nurse is developing a discharge teaching plan and reviewing priorities with the interdisciplinary team. Which of the following education points should the nurse identify as the most critical to emphasize for both the client and family?

A. Emphasize the need to monitor for increased energy and suicidal thoughts during the first few weeks of treatment: SSRIs can initially increase a client’s energy before mood improves, potentially raising the risk of acting on suicidal thoughts. Early recognition and monitoring by the client and family are essential for safety and timely intervention. B. Advise the client to report symptoms such as nausea, headache, and insomnia as possible side effects: While it is important to monitor and report common side effects, these are generally not life-threatening and are secondary to the priority of suicide risk monitoring during initial treatment. C. Reinforce the importance of taking the medication at the same time each day to maintain therapeutic levels: Consistent dosing is important for efficacy, but it is not the immediate safety priority compared with monitoring for suicidal ideation and increased energy. D. Instruct the client to avoid consuming grapefruit or grapefruit juice to prevent altered drug metabolism: Fluoxetine is not significantly affected by grapefruit, so while dietary considerations are relevant for some medications, this is not a critical teaching point for fluoxetine.