A client on Regular insulin develops lipohypertrophy at injection sites. What would the nurse instruct the patient to do?

Rationale: A. Repeatedly using the same injection site causes lipohypertrophy, which is the accumulation of fatty tissue at the injection site. This leads to uneven or delayed insulin absorption, resulting in unpredictable blood glucose levels, including sudden hyperglycemia or hypoglycemia. Injecting in the same spot may feel convenient, but it worsens tissue damage and increases the risk of long-term complications. B. Temporarily stopping insulin is extremely dangerous for patients with diabetes, especially those dependent on regular insulin. Doing so can quickly lead to hyperglycemia, diabetic ketoacidosis (DKA), or other acute complications. Insulin therapy must be continuous; missing doses is never recommended without direct medical supervision. C. Massaging areas with lipohypertrophy can further traumatize subcutaneous tissue and alter the absorption rate of insulin, increasing variability in blood glucose control. Gentle site care is important, but massage is not advised, as it can exacerbate tissue changes and reduce insulin efficacy. D. Systematic rotation of injection sites (for example, using different quadrants of the abdomen, thighs, or upper arms) prevents repeated trauma to the same area, reducing the risk of lipohypertrophy. Proper rotation improves insulin absorption consistency, helping maintain stable blood glucose levels. Patients should also inspect injection sites regularly for lumps, swelling, or skin changes, and avoid injecting into areas with existing lipohypertrophy. Education should include spacing injections at least 1 inch apart within the same site.