A client prescribed fluoxetine (Prozac) returns to the clinic one week after beginning therapy and states, "This drug is not working, I am still very sad." Which of the following would be the nurse's best response?

A. Adding another drug is premature; fluoxetine may need more time to show effects. B. While some antidepressants may show effects in 1-3 weeks, fluoxetine typically requires a full 4-6 weeks to demonstrate its therapeutic effects. C. Switching to another antidepressant after only one week may be premature; fluoxetine often takes longer to be effective. D. Antidepressants like fluoxetine generally take 4-6 weeks to show significant effects, so patience is necessary for the medication to reach its full potential.