A client receives a prescription for amoxicillin 2 g/clavulanate 125 mg by mouth every 12 hours for 10 days. The medication is available in 1000 mg/62.5 mg extended release tablets. How many tablets should the nurse administer? (Enter numerical value only.)
Explanation & Rationale
Given: Ordered dose of amoxicillin/clavulanate: 2 g amoxicillin + 125 mg clavulanate every 12 hours Available tablets: 1000 mg amoxicillin + 62.5 mg clavulanate extended-release tablets Step 1: Determine the total daily dose of amoxicillin/clavulanate: Since the medication is given every 12 hours, there are 2 administrations per day. Total daily dose (amoxicillin) = Dose per administration (amoxicillin) x Number of administrations per day Total daily dose (amoxicillin) = 2 g/dose x 2 doses/day Total daily dose (amoxicillin) = 4 g/day = 4000 mg/day Total daily dose (clavulanate) = Dose per administration (clavulanate) x Number of administrations per day Total daily dose (clavulanate) = 125 mg/dose x 2 doses/day Total daily dose (clavulanate) = 250 mg/day Step 2: Calculate the number of tablets required per day: Number of tablets/day = Total daily dose (amoxicillin) / Strength of amoxicillin per tablet Number of tablets/day = 4000 mg/day / 1000 mg/tablet Number of tablets/day = 4 tablets/day