A client receives a prescription for itraconazole. Which statement made by the client requires additional instruction by the nurse?

A. Drinking grapefruit juice will reduce the effects of the medication: Grapefruit juice can interact with itraconazole, but it typically increases rather than reduces drug levels. The client’s awareness of potential interactions is important, though clarification may be needed. B. If I experience any difficulty with breathing I will report it: Respiratory symptoms could indicate an allergic reaction or adverse effect; reporting these promptly is appropriate and demonstrates understanding. C. Monitoring for changes in stool color is important: Itraconazole can affect liver function, and changes in stool or urine may signal hepatotoxicity. Monitoring these changes is appropriate teaching. D. I should take the medication with antacids: Antacids reduce gastric acidity, which decreases itraconazole absorption and effectiveness. The client should be instructed to avoid antacids around the time of medication administration.