A client receives a prescription for methotrexate. Which information provided by the client requires additional instruction by the nurse?

Choice A reason: Storing methotrexate at room temperature is appropriate and does not require correction. This is consistent with safe handling guidelines. Choice B reason: Methotrexate is contraindicated during pregnancy because it is a folate antagonist and teratogenic, meaning it can cause severe birth defects or fetal death. Clients must be instructed to avoid pregnancy while taking methotrexate and use effective contraception. This statement requires immediate correction. Choice C reason: Obtaining a platelet count weekly is appropriate because methotrexate can cause bone marrow suppression, leading to thrombocytopenia. Monitoring platelet counts helps detect hematologic toxicity early. Choice D reason: Using folic acid supplementation is recommended to reduce methotrexate toxicity, particularly mucosal and hematologic side effects. While folic acid does not directly protect the liver, it helps mitigate adverse effects. This statement is acceptable and does not require correction.