A client receives a prescription for methotrexate. Which information provided by the client requires additional instruction by the nurse?

A. Obtain a platelet count weekly: Methotrexate can cause bone marrow suppression, leading to thrombocytopenia, leukopenia, and anemia. Regular monitoring of platelet counts and other hematologic parameters is essential to detect early signs of myelosuppression and prevent serious complications. This demonstrates correct understanding by the client. B. Use folic acid to protect the liver: Folic acid supplementation is commonly recommended to reduce methotrexate toxicity, particularly hepatotoxicity and mucosal irritation. Clients taking methotrexate should follow dosing instructions for folic acid to help protect liver function and minimize adverse effects. C. Take the medication during pregnancy: Methotrexate is teratogenic and contraindicated during pregnancy due to the high risk of fetal malformations and miscarriage. If a client reports taking or intending to take methotrexate while pregnant, the nurse must provide immediate education about the risks, contraception requirements, and alternative therapies, as this represents a critical safety concern. D. Store the medication at room temperature: Methotrexate is stable when stored at room temperature in a tightly sealed container, away from light and moisture. This client statement reflects correct understanding of safe medication storage practices and does not require correction.