A client who had a knee replacement surgery receives a prescription for enoxaparin 30 mg subcutaneously every 12 hours for 10 days. The medication is available in 30 mg per 0.3 mL prefilled syringes. How many mL should the practical nurse (PN) administer each day? (Enter numerical value only.)
Explanation & Rationale
Medication dose: 30 mg enoxaparin Medication concentration: 30 mg per 0.3 mL (prefilled syringe) Frequency: Every 12 hours Duration: 10 days Calculation: Injections per day: Since the medication is given every 12 hours, the client will receive injections 2 times per day (24 hours / 12 hours/injection). Total medication per day: To find the total amount of enoxaparin needed per day, multiply the single injection dose by the number of injections: Total enoxaparin/day = Dose per injection x Number of injections/day = 30 mg/injection x 2 injections/day = 60 mg/day Volume of medication per day: Now, we need to find the volume of solution needed to deliver the total daily dose (60 mg) based on the medication concentration (30 mg/0.3 mL). We can achieve this with a proportion: Volume (mL) / Total dose (mg) = Concentration (mg/mL) Volume (mL) = (Total dose (mg) x Concentration (mL/mg)) / Concentration (mg/mL) Plugging in the values: Volume (mL) = (60 mg x 0.3 mL/mg) / 30 mg/mL Volume (mL) = 18 mL / 30 mL/mL Simplifying: Volume (mL) = 0.6 mL Therefore, the practical nurse (PN) should administer 0.6 mL of enoxaparin each day.