A client who is admitted to the intensive care unit (ICU) with acute decompensated heart failure is receiving a continuous infusion of milrinone via a subclavian venous catheter. Which action should the nurse take when preparing to administer the first dose of IV furosemide?

A. Administer furosemide IV over ten minutes. While slow IV administration is recommended to prevent ototoxicity, the priority concern is that milrinone and furosemide are incompatible when administered in the same IV line. The nurse must first ensure separate IV access before considering the administration rate. B. Notify the healthcare provider (HCP) of the incompatibility of the two drugs. The nurse does not need to notify the HCP but should instead use a separate IV line or flush the line thoroughly before and after administration if only one access is available. Milrinone and furosemide should never be mixed, as their combination can cause precipitation, leading to catheter occlusion or embolization. C. Infuse furosemide through a central line to prevent extravasation. Furosemide can be given peripherally or centrally, but the concern here is drug incompatibility, not extravasation. Furosemide is not a vesicant, so central line administration is not required unless no peripheral access is available. D. Give furosemide through a separate IV access. Milrinone is incompatible with furosemide due to pH differences, which can lead to precipitation and potential catheter occlusion. To ensure safe administration, furosemide should be given through a separate IV line or, if no secondary access is available, the line should be flushed thoroughly before and after administration.