A client who is an alcoholic receives a prescription for disulfiram 500 mg by mouth (PO) daily. Which instruction should the nurse provide to this client?

A. Take the medication with at least 8 ounces (240 mL) of water and limit alcohol consumption while taking this medication is incorrect. Alcohol must be completely avoided while taking disulfiram, as even small amounts can cause a severe reaction (e.g., nausea, vomiting, headache, flushing, hypotension). B. Begin taking the medication immediately and take it daily, regardless of whether or not you drink alcohol is incorrect. Disulfiram should not be started until at least 12–48 hours after the last drink to prevent an acute reaction. C. Take the medication at bedtime and avoid consuming any more than one ounce of alcohol daily is incorrect. Alcohol must be strictly avoided in any amount. D. Take the medication each morning beginning 48 hours after your last drink of alcohol is correct. Disulfiram should be initiated at least 12–48 hours after the last alcohol consumption to prevent adverse reactions. The medication is usually taken in the morning to promote adherence.