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    RN HESI Pharmacology Proctored Exam

    A client who is newly diagnosed with diabetes insipidus (DI) is receiving synthetic vasopressin intravenously. Which side effect of vasopressin reported by the client should the nurse report to the healthcare provider?

    Explanation & Rationale

    Choice A Reason:Polyuria, or excessive urination, is a symptom of diabetes insipidus rather than a side effect of vasopressin. Vasopressin is used to reduce urine output in DI patients. If polyuria persists, it may indicate that the medication is not effective, but it is not a direct side effect that requires immediate reporting.Choice B Reason:Low urine specific gravity indicates dilute urine, which is a characteristic of diabetes insipidus. Vasopressin should help concentrate the urine. If low urine specific gravity persists, it may suggest that the medication is not working effectively, but it is not a side effect that necessitates urgent reporting.Choice C Reason:Polydipsia, or excessive thirst, is another symptom of diabetes insipidus. While vasopressin should help reduce this symptom by controlling urine output, persistent polydipsia may indicate inadequate treatment. However, it is not a side effect of the medication that requires immediate attention.Choice D Reason:Worsening headache is a significant side effect that should be reported to the healthcare provider. Headaches can indicate water intoxication or hyponatremia (low sodium levels), which are serious complications of vasopressin therapy. Immediate reporting is necessary to adjust the treatment and prevent further complications.

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