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    RN HESI Pharmacology Proctored Exam

    A client who is taking an oral contraceptive receives a new prescription for erythromycin. Which instruction should the nurse provide to the client?

    Explanation & Rationale

    Choice A Reason:Taking the medications at least 12 hours apart does not address the interaction between erythromycin and oral contraceptives. Erythromycin can reduce the effectiveness of oral contraceptives by increasing the metabolism of the hormones in the contraceptive, leading to a higher risk of unintended pregnancy. Therefore, simply spacing out the medications will not mitigate this risk.Choice B Reason:Stopping the oral contraceptive immediately is not advisable without consulting a healthcare provider. Abruptly discontinuing the contraceptive can lead to hormonal imbalances and unintended pregnancy. The primary concern with erythromycin is its potential to reduce the effectiveness of the contraceptive, not that it necessitates stopping the contraceptive altogether.Choice C Reason:Using an additional form of contraception is the most appropriate advice. Erythromycin can interfere with the effectiveness of oral contraceptives, so using a backup method, such as condoms, is recommended to prevent unintended pregnancy. This ensures that the client remains protected while taking both medications.Choice D Reason:Avoiding prolonged exposure to direct sunlight is not relevant to the interaction between erythromycin and oral contraceptives. While some medications can increase photosensitivity, this is not a primary concern with erythromycin in the context of contraceptive use.

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