A client who weighs 22 pounds receives a prescription for amoxicillin 50 mg/kg/day PO in divided doses every 8 hours. The bottle is label "Amoxicillin for Oral Suspension, USP 250 mg per 5 mL". How many mL should the nurse administer with each dose? (Enter numerical value only. If rounding is required, round to the nearest tenth.)

Convert the client's weight from pounds to kilograms: Weight (kg) = Weight (pounds) / 2.2 pounds/kg = 22 pounds / 2.2 pounds/kg = 10 kg Calculate the total daily dose in milligrams: Total daily dose (mg) = Prescribed dose (mg/kg/day) x Client's weight (kg) = 50 mg/kg/day x 10 kg = 500 mg/day Determine the number of doses per day: Number of doses per day = 24 hours / Frequency of doses (hours) = 24 hours / 8 hours/dose = 3 doses/day Calculate the dose to administer with each dose: Dose per administration (mg) = Total daily dose (mg) / Number of doses per day = 500 mg / 3 doses ≈ 166.67 mg Calculate the volume to administer per dose in mL: Volume per dose (mL) = Desired dose (mg) / Available concentration (mg/mL) = 166.67 mg / (250 mg / 5 mL) = 166.67 mg / 50 mg/mL ≈ 3.3 mL Rounding to the nearest tenth: = 3.3 mL