A client who weighs 45kg is ordered to receive 500 mg of amoxicillin every eight hours. The dosing range noted in the Davis Drug Guide is 20 to 40 mg/kg/day divided and to be given every 8 hours. True or False: the client's dose is safe and therapeutic?

To determine if the client's dose is safe and therapeutic, we need to calculate the appropriate dosing range based on the client's weight and compare it with the ordered dose. Client's weight: 45 kg Ordered dose: 500 mg every 8 hours, which equals 1500 mg/day (500 mg × 3 doses). Calculate the therapeutic range: The dosing range in the Davis Drug Guide is 20 to 40 mg/kg/day. So, for this client, based on their weight of 45 kg: Minimum dose: 20 mg × 45 kg = 900 mg/day Maximum dose: 40 mg × 45 kg = 1800 mg/day The ordered dose of 1500 mg/day falls within this range (900 mg/day to 1800 mg/day), which means it is safe and therapeutic for the client.