A client with a history of anaphylactic reaction to penicillin receives a prescription for cephalexin 500 mg PO twice daily. Which action should the nurse take?

A. Contact the healthcare provider (HCP): Clients with a history of anaphylaxis to penicillin have a significant risk of cross-reactivity with cephalexin, a cephalosporin. It is crucial to notify the healthcare provider to reconsider or adjust the antibiotic choice to avoid a potentially life-threatening allergic reaction. B. Monitor the client for a rash or hives: While monitoring for allergic reactions is important, the severity of a previous anaphylactic reaction warrants proactive communication with the healthcare provider before administration rather than waiting for symptoms to appear. C. Give with prescribed antihistamine: Administering an antihistamine does not prevent a severe anaphylactic reaction. It may mask mild symptoms but is not a substitute for avoiding potentially cross-reactive antibiotics. D. Administer the medication as prescribed: Administering cephalexin without addressing the history of anaphylaxis could put the client at serious risk. This action is unsafe without prior consultation with the healthcare provider.