A client with cancer is admitted to a short-term rehabilitation facility. The nurse prepares to administer the client's oral chemotherapy medications. What action by the nurse is most appropriate?

Rationale: A. While this is generally a safe practice for oral medications, it does not address the safety concern specific to chemotherapy handling. B. Never crush or split chemotherapy tablets or capsules. Doing so can aerosolize the drug and expose healthcare workers or others to toxic particles. If the client cannot swallow, the nurse should consult the provider or pharmacist for an alternative formulation or administration route. C. This is incorrect and unsafe. All cytotoxic medications require specific handling precautions as outlined in institutional and OSHA hazardous drug safety guidelines. D. Oral chemotherapy drugs are hazardous agents that can be toxic through skin absorption, inhalation, or ingestion. Nurses must wear chemotherapy-approved gloves and sometimes a gown and mask when handling, splitting, or administering these medications to prevent exposure to cytotoxic substances.