A client with draining skin lesions of the lower extremity is admitted with possible methicillin-resistant Staphylococcus aureus (MRSA). Which nursing intervention(s) should the nurse include in the plan of care (POC)? Select all that apply.

Choice A reason: Monitoring the WBC count helps assess the client’s immune response and detect systemic infection. Elevated WBCs may indicate worsening infection or sepsis, which is critical in MRSA management. Choice B reason: MRSA is transmitted through direct contact with infected skin or contaminated surfaces. Contact precautions—including gloves, gowns, and dedicated equipment—are essential to prevent spread to other clients and healthcare workers. Choice C reason: Standard precautions are always used, but wearing a mask is not routinely required for MRSA unless aerosol-generating procedures are performed. MRSA is not typically airborne, so this intervention is not prioritized. Choice D reason: Sending wound drainage for culture and sensitivity confirms the presence of MRSA and guides appropriate antibiotic therapy. It is a cornerstone of evidence-based infection management. Choice E reason: A low bacteria diet is not relevant to MRSA skin infections. MRSA is not foodborne, and dietary modifications do not influence its transmission or treatment.