A client with eczema is experiencing severe pruritus. Which PRN prescription(s) should the nurse administer? Select all that apply.

Rationale: A. Transdermal analgesic: Transdermal analgesics are formulated to relieve localized pain, not itching or inflammation. They do not address the histamine release or immune activity seen in eczema. Using them offers no therapeutic benefit for pruritus. B. Topical alcohol rub: Alcohol-based products dry out the skin and cause further irritation, which can worsen eczema symptoms. Applying alcohol increases the risk of burning and inflammation. It is not recommended for sensitive or inflamed skin. C. Topical corticosteroid: Topical corticosteroids reduce skin inflammation by suppressing local immune responses. They are standard treatment for eczema flares with severe itching. These medications soothe the skin and reduce redness and swelling. D. Oral antihistamine: Antihistamines block histamine, which contributes to allergic itching in eczema. They are useful for controlling pruritus and helping clients rest. Some types, like diphenhydramine, also have sedative effects that reduce nighttime discomfort. E. Topical scabicide: Scabicides are antiparasitic agents used to treat infestations like scabies, not eczema. They do not relieve allergic itching or inflammation. Their strong chemicals may actually worsen skin irritation in eczema patients.