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    Pharmacology proctored exam (regular)

    A client with hypertension has been prescribed losartan. After 6 weeks of therapy, the primary health care provider decides the losartan alone is not controlling the client's hypertension. What does the nurse anticipate will be added to the losartan regimen for better control of this client's hypertension?

    Explanation & Rationale

    A. Candesartan: Candesartan is another angiotensin II receptor blocker (ARB) similar to losartan, but if losartan alone is ineffective, adding another ARB would not be the first choice. Combining ARBs is not recommended due to potential increased risks of side effects. B. Hydrochlorothiazide: Hydrochlorothiazide is a thiazide diuretic commonly added to an antihypertensive regimen when blood pressure is not adequately controlled by a single medication like losartan. Diuretics help reduce blood volume, which is effective in lowering blood pressure. C. Olmesartan: Olmesartan is another ARB, like losartan, and would not be added to a regimen with losartan for better control. Combining two ARBs is not recommended due to potential additive risks of side effects, especially related to renal function and hyperkalemia. D. Antidiuretic hormone (ADH): ADH is involved in water balance and regulating blood pressure but is not used as an antihypertensive medication. It would not be added to the regimen for controlling hypertension.

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