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    HESI RN Exit Exam IV Proctored Exam
    Calculation

    A client with multiple sclerosis (MS) is receiving interferon beta-1b 0.1875 mg subcutaneously every other day. The nurse reconstitutes the vial by slowly injecting 1.2 mL of diluent into the interferon vial for a reconstituted solution of 0.25 mg/1 mL. How many mL should the nurse administer? (Enter numeric value only. If rounding is required, round to the nearest hundredth.)

    mL

    Explanation & Rationale

    Calculate the volume of the reconstituted solution that contains the prescribed dose of 0.1875 mg. Since the reconstituted solution has a concentration of 0.25 mg per 1 mL, we can set up a proportion to find the answer: (0.1875 mg / X mL) = (0.25 mg / 1 mL). Solving for X gives us X = (0.1875 mg * 1 mL) / 0.25 mg, which equals 0.75 mL. Therefore, the nurse should administer 0.75 mL of the reconstituted solution.

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