Hesi pharmacology proctored exam
Calculation
A client with neuroleptic malignant syndrome receives a prescription for dantrolene 1.5 mg/kg IV. The client weighs 132 pounds. The label on 250 mg vial reads, "Reconstitute with 5 mL sterile water for injection, USP. Reconstitution yields 50 mg/mL. How many mL should the nurse administer? (Enter numeric value only. If rounding is required, round to the nearest tenth.)
mL
Explanation & Rationale
Calculation: Convert the patient's weight from pounds (lb) to kilograms (kg). Patient weight (kg) = 132 lb / 2.2 lb/kg = 60 kg. Calculate the total dose in milligrams (mg). Total dose (mg) = Patient weight (kg) x Ordered dose (mg/kg) = 60 kg x 1.5 mg/kg = 90 mg. Available concentration = 50 mg/mL. Calculate the volume to administer in milliliters (mL). Volume to administer (mL) = Desired dose (mg) / Available concentration (mg/mL) = 90 mg / 50 mg/mL = 1.8 mL.
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