A client with peptic ulcer disease receives a new prescription for cimetidine. Which statement provided by the client requires additional instruction by the nurse?

A. Decrease cigarette use to a pack per day: Smoking stimulates gastric acid secretion and can reduce the effectiveness of cimetidine in healing peptic ulcers. Even reducing to a pack a day continues to impair treatment outcomes, so complete cessation should be encouraged. B. Notify the healthcare provider of lethargy: Lethargy may indicate central nervous system effects, which can occur with cimetidine, especially in older adults or those with renal impairment. Prompt reporting allows the provider to evaluate and adjust therapy if necessary. C. Monitor for any signs of sexual dysfunction: Cimetidine can cause reversible gynecomastia, decreased libido, and impotence due to its antiandrogenic effects. Awareness of this possible side effect allows for timely reporting and management. D. Take the medication an hour after antacids: Antacids can reduce the absorption of cimetidine. Taking cimetidine at least an hour before or after antacids helps ensure optimal drug absorption and effectiveness in reducing gastric acid secretion.