A client’s medical history reveals long-term use of benzodiazepines for anxiety disorder. The nurse knows that:

Choice A reason: Benzodiazepines are not primarily toxic to kidneys or liver when used appropriately. Choice B reason: Cardiopulmonary damage is not a direct effect of benzodiazepines. Choice C reason: Personality problems are not a recognized long-term effect of benzodiazepines. Choice D reason: Benzodiazepines carry a high risk of tolerance, dependence, and withdrawal symptoms with long-term use. This is the most important concern.